Περιγραφή

The nitric oxide (NO) NOX NO7 ports supplement category has grown to astronomical proportions in recent years, although this is really a “pre-workout” supplement category with NO-associated compounds comprising a minority percentage of the ingredients in the more popular supplement formulations. Although everyone in the sports supplement world is talking about NO, very few people really understand much about it. When the amino acid L-arginine is delivered to the endothelial cells of the inner layer of arterial walls, nitric oxide (NO) NOX NO7 is formed via the enzyme nitric oxide synthase (NOS), which means that L-arginine is a precursor of NO. Increased levels of NO cause vasodilation (widening) of blood vessels. This leads to increased blood volume (known in the bodybuilding world as “the pump”), which is sought after by bodybuilders to optimize the grueling exchange of oxygen, glucose, amino acids, creatine, waste byproducts of muscular contraction, etc., that takes place both into and out of muscle during and immediately after intense muscular contraction. It might seem logical to conclude that supplementing with L-arginine would enhance the production of NO. However, it’s more complicated than that. The body uses L-arginine for many purposes other than its role as a precursor of NOX NO7 . Also, according to the PDR® for Nutritional Supplements™, in vitro studies have shown that under normal physiological circumstances NOS is saturated with its L-arginine substrate. In other words, L-arginine would not be expected to be rate limiting for the NOS enzyme, and it would not appear that supra physiological levels of L-arginine-which would occur with oral supplementation of L-arginine-would make any difference with regard to NO production.

The reaction would appear to have reached its maximum level. However, in vivo studies have demonstrated that under certain physiological conditions, supplemental L-arginine can enhance endothelial-dependant vasodilation and NO production, possibly through mechanisms that interfere with compounds that are normally inhibitors of NOS NOX NO7. This discordance between the in vitro and in vivo results is known as the “arginine paradox”. Scientific data has not yet validated that intense muscular contraction fosters a type of physiological environment that enables supplemental L-arginine to positively influence greater activity of NOS and thus enhanced levels of NO. Despite this lack of scientific support, “real-world” anecdotal evidence, from the stomping grounds in the gyms across America, suggests that NO supplements are contributing to enhanced levels of NO. However, because the formulations in these popular NO products contain many beneficial pre-workout compounds (mostly creatine and other amino acids) that are unrelated to the production of NO, one cannot discount the extent to which these other compounds may be contributing to the vasodilation effect that has already been initiated by the body in response to intense muscular contraction.

For a moment, let’s operate under the assumption that the physiological state resulting from the onset of intense muscular contraction does tip the balance of the “norleucine” scale in favor of L-arginine enhanced NOS NOX NO7activity and NO production. The entire sports supplement industry, in its near insane NO craze, has still completely missed the boat when it comes to creating the best possible NO products, because these product formulations fail to utilize L-arginine effectively to push the real boundaries of NO production. L-arginine is easily broken down by the enzyme arginase before it can be made available to endothelial cells, which has led other supplement companies to use an “end run” approach–to bypass arginase by utilizing a precursor of L-arginine called L-arginine alpha. Unfortunately, this now brings an intermediary compound(s) into the “food chain” of NO production, which may very well result in gross inefficiency in terms of supplying optimal levels of L-arginine to the endothelial cells for NO production. AVX Sports Pharma, on the other hand, utilizes a “straight up the middle” approach by blasting high dosages of L-arginine into the bloodstream along with highly potent, arginase inhibitors that bond to arginase enzymes, which render these enzymes incapable of preventing L-arginine from uniting with NOS enzymes on their way to creating NO.

NOX NO7 Nitric oxide (NO) sports nutrition has become the largest sports nutrition product category. Yet, despite dozens of “advancements” in NO supplementation, traditional NO sports nutrition still remains flawed for one fundamental reason. This flaw can easily be detected by simply inspecting the formulations in NO products across-the-board throughout the sports nutrition industry. The formulations in these products demonstrate a failure on the part of other supplement companies to understand and address the most efficacious means to serve L-arginine up on a platter for the production of NO, which is to incapacitate the arginase enzyme. Arginase is the enzyme that breaks down arginine, which is a problem for NO supplements because arginine is the source of NO production. With the exception of Hi-Tech Pharmaceuticals, no other supplement company has figured out how to tackle the arginase problem head-on… to take arginase out of the NO equation!

Supplement Facts:
Serving Size: 6 caps
Ingredient Amount Per Serving

NOX NO7 BLEND 5000mg
2(S)-Amino-6-Bronohexanoic Acid (ABH) Norleucine,
Nitrosigine (Inositol-Arginine Silicate), Arginine NitrateNO3, Agmatine Silicate, L-Norvaline, GPLC-D-Propionyl-
Carnitin (Glycocarn), Vaso6 (White Tea Leaf),Transresveratrol.
*% Daily Value based on a 2,000 calorie diet
**Percent Daily Value Not Established